Phospho-P38 (T180 + Y182) Rabbit Polyclonal Antibody
货号:ER2001-52
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价格:
1600.00
规格:
50ul
100ul
货期:
1-3天
请注意: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Details
产品详情
  • Phospho-P38 (T180 + Y182) Rabbit Polyclonal Antibody

    概述

    产品名称

    Phospho-P38 (T180 + Y182) Rabbit Polyclonal Antibody

    抗体类型

    Rabbit Polyclonal Antibody

    免疫原

    Synthetic phospho-peptide corresponding to residues surrounding Thr180 and Y182 of human P38.

    种属反应性

    Human, Mouse, Rat

    验证应用

    WB

    分子量

    Predicted band size: 41 kDa

    阳性对照

    NIH/3T3 treated with 250ng/mL anisomycin for 30 minutes cell lysate, HeLa treated with 25μg/mL anisomycin for 30 minutes cell lysate, C6 treated with 25μg/mL anisomycin for 30 minutes cell lysate, PC-12 treated with UV for 1 hour cell lysate.

    偶联

    unconjugated

    产品特性

    形态

    Liquid

    浓度

    1ug/ul

    存放说明

    Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

    存储缓冲液

    1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

    亚型

    IgG

    纯化方式

    Immunogen affinity purified.

    应用稀释度


    • WB

    • 1:500-1:2,000

    发表文章中的应用

    靶点

    功能

    Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK14 is one of the four p38 MAPKs which play an important role in the cascades of cellular responses evoked by extracellular stimuli such as proinflammatory cytokines or physical stress leading to direct activation of transcription factors. Accordingly, p38 MAPKs phosphorylate a broad range of proteins and it has been estimated that they may have approximately 200 to 300 substrates each. Some of the targets are downstream kinases which are activated through phosphorylation and further phosphorylate additional targets.

    背景文献

    1. Deak M. et. al. Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB. EMBO J. 17:4426-4441(1998).

    亚细胞定位

    Cytoplasm, Nucleus.

    别名

    CSAID Binding Protein 1 antibody

    CSAID binding protein antibody

    CSAID-binding protein antibody

    Csaids binding protein antibody

    CSBP 1 antibody

    CSBP 2 antibody

    CSBP antibody

    CSBP1 antibody

    CSBP2 antibody

    CSPB1 antibody

    展开


Instruction manual/COA download
说明书/COA下载
Published literature
已发表文献
  • Baicalein antagonises Rhopilema esculentum toxin-induced oxidative stress and apoptosis by modulating ROS-MAPK-NF-κB and inhibiting PLA2 activity

    Author: Zengfa Wang, Fengling Yang, Yi Wang, Xiaoyu Geng, Jinyu Zhang, Xinming Wang, Chang Liu, Blessing Danso, Jingbo Chen, Marina Pozzolini, Xianpeng Zu, Liang Xiao, Jing Zhang

    PMID: 39880047

    期刊: Toxicon

    应用: WB

     

    反应种属: Mouse

     

    发表时间: 2025 Jan

    http://pubmed.ncbi.nlm.nih.gov/39880047/

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